09
06
2017
Repeated dose toxicity studies is the core of non-clinical safety evaluation of drugs, it is acute toxicity, reproductive toxicity and carcinogenicity and other toxicology research, closely linked to the drug from the pharmaceutical research into clinical trials.
09
06
2017
For the development of innovative drugs, the process consists of three stages and four steps: target discovery, characterization and evaluation (biological target phase); discovery and optimization of lead compounds (drug discovery phase).
09
06
2017
Non-clinical pharmacokinetic studies are based on animal, external and human research methods to reveal the dynamic changes in drugs in vivo, to obtain the basic pharmacokinetic parameters of drugs to elucidate the absorption, distribution, metabolism and excretion of drugs process and characteristics.
09
05
2017
Researchers report the discovery of an important role for the RSF1, or remodeling and spacing factor 1, protein in silencing genes.
09
05
2017
Scientists concluded that the aberrantly assembled proteins were the result of certain metabolic disorders, but new evidence suggests that the cell's response to unfolded or misfolded proteins could be a cause, rather than a consequence, of metabolic disorders.
